Our Statistics

Updated important Research Findings from Hong Kong Hereditary Breast Cancer Family Registry (Analysis of Participants recruited into research study till September 2016):

Analysis of 2117 breast cancer or ovarian cancer patients who are clinically considered high risk based on young age at diagnosis, multiple members with breast/ovarian/prostate and BRCA related cancers in the family. 


The average age of women referred for genetic counselling and testing is 48.2 years old, which is at a post-menopausal age. 30.7% of them had age of diagnosis younger than 40 years old. 


BRCA mutation was found in 9.3% of patients (197 patients), of which 82 (41.6%) were BRCA1 mutation while the remaining 115 (58.4%) were BRCA2 mutation. This is noticeably different from patients from the Western world where majority of mutations are BRCA1 mutations.

Among these mutations SIX FOUNDER mutations in Chinese have been found. The REGISTRY is the first to report this finding and these 6 founder mutations accounts for 17.8% of all the BRCA mutations.

Among the 197 BRCA mutation carriers we also tested 398 of their family members. 187 (47.0%) of them were tested with positive result which included cancer patients and non-cancer patients.